Endothelial damage from cytomegalovirus-specific host immune response can be prevented by targeted disruption of fractalkine-CX3CR1 interaction.

Abstract

Human cytomegalovirus (CMV) infection has been linked to inflammatory diseases, including vascular disease and chronic transplant rejection, that involve vascular endothelial damage. We have previously shown that the host CD4(+) T-cell response to CMV antigen can produce IFNgamma and TNFalpha at levels sufficient to drive induction of fractalkine, a key… (More)

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Cite this paper

@article{BolovanFritts2008EndothelialDF, title={Endothelial damage from cytomegalovirus-specific host immune response can be prevented by targeted disruption of fractalkine-CX3CR1 interaction.}, author={Cynthia A Bolovan-Fritts and Stephen A. Spector}, journal={Blood}, year={2008}, volume={111 1}, pages={175-82} }