Endothelial damage and angiogenesis in hypertensive patients: relationship to cardiovascular risk factors and risk factor management.

@article{Felmeden2003EndothelialDA,
  title={Endothelial damage and angiogenesis in hypertensive patients: relationship to cardiovascular risk factors and risk factor management.},
  author={Dirk C Felmeden and Charles G C Spencer and Funmi M Belgore and Andrew D. Blann and D. Gareth Beevers and Gregory Y. H. Lip},
  journal={American journal of hypertension},
  year={2003},
  volume={16 1},
  pages={11-20}
}
BACKGROUND Hypertensive patients are at particular risk of cardiovascular complications, possibly related to endothelial damage or dysfunction, or to abnormal angiogenesis. These pathophysiologic processes are assessable by measurement of plasma levels of von Willebrand factor (vWf), and by vascular endothelial growth factor (VEGF) and its soluble receptor (sFlt-1). We hypothesized that these markers would correlate with the Framingham cardiovascular risk score and would be responsive to… CONTINUE READING

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