Endothelial cellular response to altered shear stress.

  title={Endothelial cellular response to altered shear stress.},
  author={Aron B. Fisher and Shu Chien and Abdul I Barakat and Robert M. Nerem},
  journal={American journal of physiology. Lung cellular and molecular physiology},
  volume={281 3},
Endothelial cells are normally exposed constantly to mechanical forces that significantly influence their phenotype. This symposium presented recent information concerning endothelial cell responses to shear stress associated with blood flow. Endothelial cell shear stress mechanosensors that have been proposed include membrane receptor kinases, integrins, G proteins, ion channels, intercellular junction proteins, membrane lipids (e.g., those associated with caveolae), and the cytoskeleton… CONTINUE READING


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