Endothelial cells organize fibrin clots into structures that are more resistant to lysis.

@article{Jerome2005EndothelialCO,
  title={Endothelial cells organize fibrin clots into structures that are more resistant to lysis.},
  author={W. Gray Jerome and Stefan Handt and Roy R. Hantgan},
  journal={Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada},
  year={2005},
  volume={11 3},
  pages={268-77}
}
Acute myocardial infarction is a major cause of death and disability in the United States. Introducing thrombolytic agents into the clot to dissolve occlusive coronary artery thrombi is one method of treatment. However, despite advances in our knowledge of thrombosis and thrombolysis, survival rates following thrombolytic therapy have not improved substantially. This failure highlights the need for further study of the factors mediating clot stabilization. Using laser scanning confocal… CONTINUE READING

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