Endothelial cells in chorionic fetal vessels of first trimester placenta express HLA-G.

@article{Blaschitz1997EndothelialCI,
  title={Endothelial cells in chorionic fetal vessels of first trimester placenta express HLA-G.},
  author={Astrid Blaschitz and Françoise Lenfant and Val{\'e}rie Mallet and Michaele Hartmann and Armand Bensussan and Daniel E. Geraghty and Philippe Le Bouteiller and Gottfried Dohr},
  journal={European journal of immunology},
  year={1997},
  volume={27 12},
  pages={3380-8}
}
Using four different HLA-G-recognizing monoclonal antibodies (mAb), we investigated whether this nonclassical HLA class I molecule could be expressed in placental cell types other than extravillous cytotrophoblasts (evct) in which HLA-G has already been detected. Immunohistochemical analysis was performed on serial cryosections of first trimester placenta as well as on maternal decidual tissue. In addition to some proliferative evct, the recently described BFL.1 mAb also slightly stained some… CONTINUE READING

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