Endothelial cell-derived semaphorin 3A inhibits filopodia formation by blood vascular tip cells.

@article{Ochsenbein2016EndothelialCS,
  title={Endothelial cell-derived semaphorin 3A inhibits filopodia formation by blood vascular tip cells.},
  author={Alexandra Michaela Ochsenbein and Sinem Karaman and Steven T Proulx and Michaela Berchtold and Giorgia Jurisic and Esther T Stoeckli and Michael Detmar},
  journal={Development},
  year={2016},
  volume={143 4},
  pages={589-94}
}
Vascular endothelial growth factor (VEGF)-A is a well-known major chemoattractant driver of angiogenesis--the formation of new blood vessels from pre-existing ones. However, the repellent factors that fine-tune this angiogenic process remain poorly characterized. We investigated the expression and functional role of endothelial cell-derived semaphorin 3A… CONTINUE READING