Endothelial cell co-culture mediates maturation of human embryonic stem cell to pancreatic insulin producing cells in a directed differentiation approach.

@article{Jaramillo2012EndothelialCC,
  title={Endothelial cell co-culture mediates maturation of human embryonic stem cell to pancreatic insulin producing cells in a directed differentiation approach.},
  author={Maria Jaramillo and Ipsita Banerjee},
  journal={Journal of visualized experiments : JoVE},
  year={2012},
  volume={61}
}
Embryonic stem cells (ESC) have two main characteristics: they can be indefinitely propagated in vitro in an undifferentiated state and they are pluripotent, thus having the potential to differentiate into multiple lineages. Such properties make ESCs extremely attractive for cell based therapy and regenerative treatment applications. However for its full potential to be realized the cells have to be differentiated into mature and functional phenotypes, which is a daunting task. A promising… CONTINUE READING
8 Citations
15 References
Similar Papers

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-10 of 15 references

Les cellules souches embryonnaires humaines : de la transgression de l ' embryon humain á la médecine régénératrice de demain

  • J. De Vos, S. Assou, S. Tondeur, M. Dijon, S. Hamamah
  • Gynécologie Obstétrique & Fertilité .
  • 2009

de la transgression de l'embryon humain á la médecine régénératrice de demain

  • J. De Vos, S. Assou, S. Tondeur, M. Dijon, Hamamah, S. Les cellules souches embryonnaires humaines
  • Gynécologie Obstétrique & Fertilité. 37, 620-626
  • 2009

Directed Differentiation of Human Embryonic Stem Cells into the Pancreatic Endocrine Lineage

  • B. W. Phillips, H. Hentze, +13 authors N. R. Dunn
  • Stem Cells and Development
  • 2007

Similar Papers

Loading similar papers…