Endothelial Sphingosine 1‑Phosphate Receptor‑1 Mediates Protection and Recovery from Acute Kidney Injury.

Abstract

Epithelial and endothelial injury and a cascade of immune and interstitial cell activation in the kidney lead to AKI. After mild to moderate AKI, the epithelium can regenerate and restore kidney function, yet little is known about the endothelium during these repair processes. Sphingosine 1-phosphate receptor 1 (S1P1), a G protein-coupled receptor, is… (More)

Topics

Cite this paper

@article{Perry2016EndothelialS1, title={Endothelial Sphingosine 1‑Phosphate Receptor‑1 Mediates Protection and Recovery from Acute Kidney Injury.}, author={Heather M Perry and Liping Huang and Hong Ye and Chong Liu and Sun-Sang J Sung and Kevin R. Lynch and Diane. L. Rosin and Amandeep Bajwa and Mark Douglas Okusa}, journal={Journal of the American Society of Nephrology : JASN}, year={2016}, volume={27 11}, pages={3383-3393} }