Endothelial Semaphorin 7A promotes neutrophil migration during hypoxia.

@article{MoroteGarcia2012EndothelialS7,
  title={Endothelial Semaphorin 7A promotes neutrophil migration during hypoxia.},
  author={Julio C{\'e}sar Morote-Garcia and Daniel Napiwotzky and David A. Koehler and Peter Rosenberger},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2012},
  volume={109 35},
  pages={14146-51}
}
Recent studies identified basic biological principles that are shared by the immune and the nervous system. One of these analogies applies to the orchestration of cellular migration where guidance proteins that serve as a stop signal for axonal migration can also serve as a stop signal for the migration of immune-competent cells. The control of leukocyte migration is of key interest during conditions associated with inflammatory tissue changes such as tissue hypoxia or hypoxic inflammation… CONTINUE READING
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Hypoxia-inducible factor-dependent induction of netrin-1 dampens inflammation caused by hypoxia

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