Endothelial Claudin

@article{Morita1999EndothelialC,
  title={Endothelial Claudin},
  author={Kazumasa Morita and Hiroyuki Sasaki and Mikio Furuse and Shoichiro Tsukita},
  journal={The Journal of Cell Biology},
  year={1999},
  volume={147},
  pages={185 - 194}
}
Tight junctions (TJs) in endothelial cells are thought to determine vascular permeability. Recently, claudin-1 to -15 were identified as major components of TJ strands. Among these, claudin-5 (also called transmembrane protein deleted in velo-cardio-facial syndrome [TMVCF]) was expressed ubiquitously, even in organs lacking epithelial tissues, suggesting the possible involvement of this claudin species in endothelial TJs. We then obtained a claudin-6-specific polyclonal antibody and a… CONTINUE READING

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