Endothelial Cells as Precursors for Osteoblasts in the Metastatic Prostate Cancer Bone

Abstract

Prostate cancer cells metastasize to the bones, causing ectopic bone formation, which results in fractures and pain. The cellular mechanisms underlying new bone production are unknown. In a recent study, Lin and colleagues, by using state-of-the-art techniques, including prostate cancer mouse models in combination with sophisticated in vivo lineage-tracing… (More)
DOI: 10.1016/j.neo.2017.08.007

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