Endothelial, platelet and leukocyte interactions in ischemic heart disease: insights into potential mechanisms and their clinical relevance.

@article{Dinerman1990EndothelialPA,
  title={Endothelial, platelet and leukocyte interactions in ischemic heart disease: insights into potential mechanisms and their clinical relevance.},
  author={J L Dinerman and Jawahar Lal Mehta},
  journal={Journal of the American College of Cardiology},
  year={1990},
  volume={16 1},
  pages={207-22}
}
Recent investigations of the complex interactions among vascular endothelium, platelets and leukocytes have relevance to the pathogenesis of atherosclerosis and ischemic heart disease. Perturbations in the hemodynamic equilibrium maintained by these cellular elements may lead to vasospasm, in vivo thrombosis and a reduction in blood flow. Recent advances in the understanding of these interactions in health and disease states are summarized. The effect of pharmacologic agents on these cell-cell… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 36 extracted citations

Pan Vascular Medicine

Springer Berlin Heidelberg • 2002
View 10 Excerpts
Highly Influenced

Effects of thrombocytopenia and shear rate on neutrophil and platelet deposition on endothelial and medial arterial surfaces.

Arteriosclerosis and thrombosis : a journal of vascular biology • 1993
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…