Endosome-associated CRT1 functions early in resistance gene-mediated defense signaling in Arabidopsis and tobacco.

@article{Kang2010EndosomeassociatedCF,
  title={Endosome-associated CRT1 functions early in resistance gene-mediated defense signaling in Arabidopsis and tobacco.},
  author={Hong-Gu Kang and Chang-Sik Oh and Masanao Sato and Fumiaki Katagiri and Jane Glazebrook and Hideki Takahashi and Pradeep Kachroo and Gregory B Martin and Daniel F Klessig},
  journal={The Plant cell},
  year={2010},
  volume={22 3},
  pages={918-36}
}
Resistance gene-mediated immunity confers protection against pathogen infection in a wide range of plants. A genetic screen for Arabidopsis thaliana mutants compromised for recognition of turnip crinkle virus previously identified CRT1, a member of the GHKL ATPase/kinase superfamily. Here, we demonstrate that CRT1 interacts with various resistance proteins from different structural classes, and this interaction is disrupted when these resistance proteins are activated. The Arabidopsis mutant… CONTINUE READING
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