Endoscopy-negative reflux disease: what is the value of a proton-pump inhibitor test in everyday clinical practice?

@article{JuulHansen2003EndoscopynegativeRD,
  title={Endoscopy-negative reflux disease: what is the value of a proton-pump inhibitor test in everyday clinical practice?},
  author={Paul Juul-Hansen and Andreas Rydning},
  journal={Scandinavian journal of gastroenterology},
  year={2003},
  volume={38 12},
  pages={1200-3}
}
BACKGROUND Our aim in this study was to evaluate a simple test with proton-pump inhibitor (PPI) for use in everyday clinical practice in diagnosing endoscopy-negative reflux disease. METHODS 68 patients with heartburn and/or acid regurgitation as their main complaint, symptoms of at least 3 months' duration prior to inclusion, all with a negative gastroscopy were included. The patients were given 60 mg of lansoprazole before breakfast for 7 days. After the test week, patients had to answer… CONTINUE READING