Endoscopic molecular imaging of human bladder cancer using a CD47 antibody

@article{Pan2014EndoscopicMI,
  title={Endoscopic molecular imaging of human bladder cancer using a CD47 antibody},
  author={Ying Pan and Jens-Peter Volkmer and Kathleen E. Mach and Robert V. Rouse and Jen-Jane Liu and Debashis Sahoo and Timothy Chang and Thomas J. Metzner and Lei Kang and Matt van de Rijn and Eila Curlee Skinner and Sanjiv Sam Gambhir and Irving L Weissman and Joseph C. Liao},
  journal={Science Translational Medicine},
  year={2014},
  volume={6},
  pages={260ra148-260ra148}
}
A combination of optical imaging technologies with cancer-specific molecular imaging agents is a potentially powerful strategy to improve cancer detection and enable image-guided surgery. Bladder cancer is primarily managed endoscopically by white light cystoscopy with suboptimal diagnostic accuracy. Emerging optical imaging technologies hold great potential for improved diagnostic accuracy but lack imaging agents for molecular specificity. Using fluorescently labeled CD47 antibody (anti-CD47… CONTINUE READING

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