Endoscopic ablation therapy for gastrointestinal superficial neoplasia.


AIM   In Japan, endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) have been widely accepted and standardized for the treatment of gastrointestinal superficial neoplasia. METHODS   In contrast, mucosal ablation techniques are more common in Western countries and a variety of endoscopic ablation modalities, including argon plasma coagulation (APC), photodynamic therapy (PDT) and lasers, are used. RESULTS   Recently developed modalities such as radiofrequency ablation (RFA) and cryotherapy are also available for the treatment of superficial lesions such as dysplasia of Barrett's esophagus. CONCLUSION   Although we should understand that the completeness of destruction of neoplastic tissue can only be judged at follow up, endoscopic ablation is a viable alternative to endoscopic resection for dysplasia and early-stage malignancies, especially for poor candidates of surgery or endoscopic resection.

DOI: 10.1111/j.1443-1661.2011.01227.x

Cite this paper

@article{Muguruma2012EndoscopicAT, title={Endoscopic ablation therapy for gastrointestinal superficial neoplasia.}, author={Naoki Muguruma and Koichi Okamoto and Tetsuo Kimura and Kazuhiro Kishi and Toshiya Okahisa and Seisuke Okamura and Tetsuji Takayama}, journal={Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society}, year={2012}, volume={24 3}, pages={139-49} }