Endoscopic Palliation of Pancreatic Cancer

  title={Endoscopic Palliation of Pancreatic Cancer},
  author={Vishal B. Gohil and Jason B. Klapman},
  journal={Current Treatment Options in Gastroenterology},
  • V. Gohil, J. Klapman
  • Published 9 August 2017
  • Medicine
  • Current Treatment Options in Gastroenterology
Opinion statementPancreas cancer is a fourth-leading cause of cancer death in the USA and its incidence is rising as the population is aging. The majority of patients present at an advanced stage due to the silent nature of the disease and treatment have focused more on palliation than curative intent. Gastroenterologists have become integral in the multidisciplinary care of these patients with a focus on providing endoscopic palliation of pancreas cancer. The three most common areas that… 
5 Citations
Endoscopic retrograde cholangiopancreatography guided interventions in the management of pancreatic cancer
Endoscopic retrograde cholangiopancreatography-guided diagnosis and therapeutic interventions play a pivotal role in the management of advanced pancreatic cancer and are increasingly used due to improved morbidity and complication rates compared to surgical management.
Pain in pancreatic ductal adenocarcinoma: A multidisciplinary, International guideline for optimized management.
  • A. Drewes, C. Campbell, R. Talukdar
  • Medicine
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
  • 2018
Endoscopic ultrasound (EUS) and the management of pancreatic cancer
This review aims to highlight the diagnostic and therapeutic role of EUS in the management of patients with pancreatic malignancy, especially pancreatic ductal adenocarcinoma.
Effect of Early Management on Pain and Depression in Patients with Pancreatobiliary Cancer: A Randomized Clinical Trial
Although the primary outcome was not met, this trial indicates that EPC may improve early pain relief in patients with advanced pancreatobiliary cancers.


Palliation of malignant extrahepatic biliary obstruction with plastic versus expandable metal stents: An evidence-based approach.
Diagnostic approach to pancreatic cancer.
EUS-guided celiac plexus interventions in pancreatic cancer pain: An update and controversies for the endosonographer
The objective is to review the use of EUS-CPN in PDAC, including a description of different techniques, review of its efficacy, predictors of pain response, and describe its limitations and safety, as well as new developments.
Endoscopic palliation of malignant gastric outlet obstruction using self-expanding metal stents: experience in 36 patients
Self-expanding metal stents are a safe and efficacious method for palliating malignant gastric outlet obstruction and restoring the ability to eat in patients seen in the setting of a variety of cancers.
Malignant gastric outlet obstruction managed by endoscopic stenting: a prospective single-centre study
Palliative stenting for advanced malignant upper GI-tract tumours at a tertiary Hepato-Pancreato-Biliary Unit is a safe, feasible and effective alternative to surgical bypass with a short hospital stay and prompt improvement of food intake.
Comparison of uncovered and covered stents for the treatment of malignant duodenal obstruction caused by pancreaticobiliary cancer
The use of uncovered stents may be a preferred option for duodenal obstruction secondary to pancreaticobiliary malignancies, since they were effective in preventing stent migration and tended to have longer patency than covered stents.
Malignancy is the most common cause of gastric outlet obstruction in the era of H2 blockers.
The incidence of malignancy in patients presenting with gastric outlets obstruction is greater than 50%, and the etiology of gastric outlet obstruction cannot be predicted by age, history of peptic ulcer disease, or nonsteroidal anti-inflammatory drug use.