Endoscopic, Deep Mural Implantation of Enteryx for the Treatment of GERD: 6-Month Follow-up of a Multicenter Trial

@article{Johnson2003EndoscopicDM,
  title={Endoscopic, Deep Mural Implantation of Enteryx for the Treatment of GERD: 6-Month Follow-up of a Multicenter Trial},
  author={David S. Johnson and Robert A. Ganz and James Aisenberg and Lawrence B. Cohen and Jacques Devi{\'e}re and T Raymond Foley and Gregory B. Haber and Jeffrey H. Peters and Glen A. Lehman},
  journal={American Journal of Gastroenterology},
  year={2003},
  volume={98},
  pages={250-258}
}
OBJECTIVES:This prospective, multicenter, single-arm study evaluated the safety and efficacy of the endoscopic implantation of Enteryx, a biocompatible, non-biodegradable liquid polymer for the treatment of GERD.METHODS:Eighty-five patients with heartburn symptoms responsive to proton pump inhibitor (PPI) use were enrolled. Inclusion requirements were HRQL score ≤ 11 on PPI and ≥ 20 off PPI, and 24-hour PH probe with ≥ 5% total time at PH ≤ 4. Patients with a hiatus hernia > 3 cm, grade 3 or 4… CONTINUE READING