Corpus ID: 92277097

Endorphins-A Forgotten Hidden Magic Holistic Healer: Mini Review

  title={Endorphins-A Forgotten Hidden Magic Holistic Healer: Mini Review},
  author={Shrihari Tg},
Endorphins are endogenous morphine, neuropeptides, synthesized in pituitary gland in response to stress and pain mediated release of CRH (Corticotropic releasing hormone) from hypothalamus activate the release of neuropeptides such as ACTH (Adreno corticotropic hormone), cortisol and noradrenaline. These neuropeptides activate inflammatory mediators such as IL1β, TNF-α, IL-6 and COX-2 inflammatory mediators activate key transcription factors such as NF-kB, STAT-3, involved in tumor progression… 

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