Endoreplication: polyploidy with purpose.

@article{Lee2009EndoreplicationPW,
  title={Endoreplication: polyploidy with purpose.},
  author={Hyun Ok Lee and Jean M. Davidson and Robert J Duronio},
  journal={Genes & development},
  year={2009},
  volume={23 21},
  pages={
          2461-77
        }
}
A great many cell types are necessary for the myriad capabilities of complex, multicellular organisms. One interesting aspect of this diversity of cell type is that many cells in diploid organisms are polyploid. This is called endopolyploidy and arises from cell cycles that are often characterized as "variant," but in fact are widespread throughout nature. Endopolyploidy is essential for normal development and physiology in many different organisms. Here we review how both plants and animals… CONTINUE READING

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References

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The origin recognition complex is dispensable for endoreplication in Drosophila.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2008
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Intrinsic negative cell cycle regulation provided by PIP boxand Cul 4 Cdt 2mediated destruction of E 2 f 1 during S phase

ST Shibutani, AF delaCruz, +4 authors RJ Duronio
  • Dev Cell
  • 2008
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL