Endoplasmic reticulum stress-induced hepatic stellate cell apoptosis through calcium-mediated JNK/P38 MAPK and Calpain/Caspase-12 pathways

Abstract

Recent reports considered that it was the disturbance of calcium homeostasis and the accumulation of misfolded proteins in the endoplasmic reticulum (ER) that activated hepatic stellate cells (HSCs) apoptosis and promoted fibrosis resolution. However, the signal-transducing events that are activated by ER stress after HSCs activation were incompletely… (More)
DOI: 10.1007/s11010-014-2073-8

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Cite this paper

@article{Huang2014EndoplasmicRS, title={Endoplasmic reticulum stress-induced hepatic stellate cell apoptosis through calcium-mediated JNK/P38 MAPK and Calpain/Caspase-12 pathways}, author={Yan Huang and Xiaohui Li and Yarui Wang and Huan Wang and Cheng Huang and Jun Li}, journal={Molecular and Cellular Biochemistry}, year={2014}, volume={394}, pages={1-12} }