Endoplasmic reticulum stress in the kidney

  title={Endoplasmic reticulum stress in the kidney},
  author={Masanori Kitamura},
  journal={Clinical and Experimental Nephrology},
Endoplasmic reticulum (ER) stress is involved in a wide range of pathological circumstances including neurodegenerative disorders, diabetes mellitus, ischemic injury, cancers, atherosclerosis, inflammation, infection, toxicity of chemicals and metals, and psychotic diseases. ER stress is also involved in some physiological events including development of particular cell types. A number of pathophysiological triggers cause accumulation of unfolded proteins in the ER, i.e., ER stress. In response… CONTINUE READING


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