Endoplasmic reticulum stress in cerebral ischemia.

  title={Endoplasmic reticulum stress in cerebral ischemia.},
  author={Qing Xin and Bingyuan Ji and Baohua Cheng and Chunmei Wang and Haiqing Liu and Xiaoyu Chen and Jinghua Chen and Bo Bai},
  journal={Neurochemistry international},
The endoplasmic reticulum (ER) stress is an essential step in the progression of brain ischemia/reperfusion (I/R) injury. It is possible that the timing of events for ER stress signaling regulation is important for the balance of life and death such that ER stress is initially protective, aiming to restore ER homeostasis, whereas prolonged periods of ER stress can be deleterious and damaging. Nevertheless, modulation of ER stress exerts a remarkable protective effect on the ischemic brain and… CONTINUE READING
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  • Q. Xin
  • Neurochemistry International
  • 2014
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