Endoplasmic reticulum stress and apoptosis

  title={Endoplasmic reticulum stress and apoptosis},
  author={Jitka Faitova and Daniel Krekac and Roman Hrstka and Borivoj Vojtesek},
  journal={Cellular & Molecular Biology Letters},
Cell death is an essential event in normal life and development, as well as in the pathophysiological processes that lead to disease. It has become clear that each of the main cellular organelles can participate in cell death signalling pathways, and recent advances have highlighted the importance of the endoplasmic reticulum (ER) in cell death processes. In cells, the ER functions as the organelle where proteins mature, and as such, is very responsive to extracellular-intracellular changes of… CONTINUE READING

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