Endoplasmic reticulum stress: a novel mechanism and therapeutic target for cardiovascular diseases

@article{Liu2016EndoplasmicRS,
  title={Endoplasmic reticulum stress: a novel mechanism and therapeutic target for cardiovascular diseases},
  author={Mei-qing Liu and Zhe Chen and Lin-xi Chen},
  journal={Acta Pharmacologica Sinica},
  year={2016},
  volume={37},
  pages={425-443}
}
Endoplasmic reticulum is a principal organelle responsible for folding, post-translational modifications and transport of secretory, luminal and membrane proteins, thus palys an important rale in maintaining cellular homeostasis. Endoplasmic reticulum stress (ERS) is a condition that is accelerated by accumulation of unfolded/misfolded proteins after endoplasmic reticulum environment disturbance, triggered by a variety of physiological and pathological factors, such as nutrient deprivation… CONTINUE READING

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