Endoplasmic Reticulum Stress Aggravates Viral Myocarditis by Raising Inflammation Through the IRE1-Associated NF-κB Pathway.

@article{Zha2015EndoplasmicRS,
  title={Endoplasmic Reticulum Stress Aggravates Viral Myocarditis by Raising Inflammation Through the IRE1-Associated NF-κB Pathway.},
  author={Xi Liang Zha and Yan Yue and Ning Dong and Sidong Xiong},
  journal={The Canadian journal of cardiology},
  year={2015},
  volume={31 8},
  pages={1032-40}
}
BACKGROUND Viral myocarditis, which is mostly caused by coxsackievirus infection, is characterized by myocardial inflammation. Abnormal endoplasmic reticulum (ER) stress participates in many heart diseases, but its role in viral myocarditis remains unsolved. METHODS We investigated the influence of ER stress in coxsackievirus B3 (CVB3)-induced viral… CONTINUE READING