Endoplasmic Reticulum Stress, Genome Damage, and Cancer

@inproceedings{Dicks2015EndoplasmicRS,
  title={Endoplasmic Reticulum Stress, Genome Damage, and Cancer},
  author={Naomi Dicks and Karina Andrade Guti{\'e}rrez and Marek Michalak and Vilceu Bordignon and Luis B. Agellon},
  booktitle={Front. Oncol.},
  year={2015}
}
Endoplasmic reticulum (ER) stress has been linked to many diseases, including cancer. A large body of work has focused on the activation of the ER stress response in cancer cells to facilitate their survival and tumor growth; however, there are some studies suggesting that the ER stress response can also mitigate cancer progression. Despite these contradictions, it is clear that the ER stress response is closely associated with cancer biology. The ER stress response classically encompasses… CONTINUE READING

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