Endoplasmic Reticulum Ca(2+) Handling and Apoptotic Resistance in Tumor-Derived Endothelial Colony Forming Cells.

@article{Poletto2016EndoplasmicRC,
  title={Endoplasmic Reticulum Ca(2+) Handling and Apoptotic Resistance in Tumor-Derived Endothelial Colony Forming Cells.},
  author={Valentina Poletto and Silvia Dragoni and Dmitry Lim and Marco Biggiogera and Adele Aronica and Maria Pia Cinelli and Antonio De Luca and Vittorio Rosti and Camillo Porta and Germano Guerra and Francesco Moccia},
  journal={Journal of cellular biochemistry},
  year={2016},
  volume={117 10},
  pages={
          2260-71
        }
}
Truly endothelial progenitor cells (EPCs) can be mobilized from bone marrow to support the vascular network of growing tumors, thereby sustaining the metastatic switch. Endothelial colony forming cells (ECFCs) are the only EPC subtype belonging to the endothelial phenotype and capable of incorporating within neovessels. The intracellular Ca(2+) machinery plays a key role in ECFC activation and is remodeled in renal cellular carcinoma-derived ECFCs (RCC-ECFCs). Particularly, RCC-ECFCs seems to… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 48 REFERENCES

Caspase-3 and -9 are activated in human myeloid HL-60 cells by calcium signal

  • Molecular and Cellular Biochemistry
  • 2009
VIEW 12 EXCERPTS
HIGHLY INFLUENTIAL

Remodelling of Ca2+ transport in cancer: how it contributes to cancer hallmarks?

  • Philosophical transactions of the Royal Society of London. Series B, Biological sciences
  • 2014
VIEW 9 EXCERPTS
HIGHLY INFLUENTIAL