Endophilin-1 regulates blood-brain barrier permeability via EGFR-JNK signaling pathway.

@article{Chen2015Endophilin1RB,
  title={Endophilin-1 regulates blood-brain barrier permeability via EGFR-JNK signaling pathway.},
  author={Lin Chen and Wenjing Liu and Ping Wang and Yi-xue Xue and Qingjie Su and Chaosheng Zeng and Xiuli Shang},
  journal={Brain research},
  year={2015},
  volume={1606},
  pages={44-53}
}
Endophilin-1 (Endo1), a multifunctional protein, is essential for synaptic vesicle endocytosis. However, the role and mechanism of endophilin-1 in blood-brain barrier (BBB) function are still unclear. This study was performed to determine whether endophilin-1 regulated BBB permeability via the EGFR-JNK signaling pathway. In the present study, we found that… CONTINUE READING