Endopeptidases and prohormone processing.

@article{Darby1990EndopeptidasesAP,
  title={Endopeptidases and prohormone processing.},
  author={Nigel J Darby and Derek G. Smyth},
  journal={Bioscience reports},
  year={1990},
  volume={10 1},
  pages={1-13}
}
Peptide hormones and peptide transmitters are generated from polypeptide precursors by specific cleavage reactions which take place principally at sites formed by single or paired basic residues. Not all the possible cleavage sites are utilised, however, and the degree of processing of many propeptides has been found to vary according to the tissue of… CONTINUE READING