Endomyocardial infiltration by B and NK cells foreshadows the recurrence of cardiac allograft rejection.

@article{Sorrentino2006EndomyocardialIB,
  title={Endomyocardial infiltration by B and NK cells foreshadows the recurrence of cardiac allograft rejection.},
  author={Carlo Sorrentino and A Scarinci and Tommaso D'antuono and Marcelo Piccirilli and Marco Di Nicola and Marian M. Pasquale and Cesare Di Iorio and Emma Di Carlo},
  journal={The Journal of pathology},
  year={2006},
  volume={209 3},
  pages={400-10}
}
Heart allograft outcome is unpredictable and acute rejection episodes still occur despite the improvement of immunosuppressive regimens. We therefore investigated whether the immunopathological profile of endomyocardial biopsies might underlie the variations in the clinical course of a graft. Biopsies from transplanted patients were analysed by histology, immunohistochemistry (associated with digital image analysis), confocal and electron microscopy to determine the type and the functional… CONTINUE READING

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