Endometriosis and Infertility

  title={Endometriosis and Infertility},
  author={Sebiha Ozdemir Ozkan and William K Murk and Aydın Arıcı},
  journal={Annals of the New York Academy of Sciences},
Endometriosis is an estrogen‐dependent disorder defined as the presence of endometrial tissue outside of the uterine cavity. A leading cause of infertility, endometriosis has a prevalence of 0.5–5% in fertile and 25–40% in infertile women. The optimal choice of management for endometriosis‐associated infertility remains obscure. Removal or suppression of endometrial deposits by medical or surgical means constitutes the basis of endometriosis management. Current evidence indicates that… 

Infertility Treatment of Endometriosis Patients

Evidence concerning infertility treatment of endometriosis patients is summarized and the decision about whether to undergo laparoscopy or superovulation with intrauterine insemination (IUI) or pursue ART will depend on a variety of factors such as the patient’s age and symptoms, other infertility factors, risk of surgery, the presence of Endometrioma, and ovarian reserve.

Management of women affected by endometriosis: Are we stepping forward?

Due to the worldwide acceptance and the ongoing evolution of minimally invasive surgery to treat both benign and malignant diseases, future investigations may be conducted to consider this approach to save the function of all the organs involved by the disease and to reduce post-operative discomfort and psychological impact.

Clinical Management of Endometriosis.

  • T. Falcone
  • Medicine
    Seminars in reproductive medicine
  • 2017
The different types of peritoneal disease found in endometriosis patients are presented and the technique used to safely and completely remove the disease is discussed.

Clinical management of endometriosis.

The different types of peritoneal disease found in endometriosis patients are presented and the technique used to safely and completely remove the disease is discussed.

Evaluation and treatment of endometriosis.

Diagnosis of endometriosis in primary care is predominantly clinical and common agents used for primary dysmenorrhea, such as nonsteroidal anti-inflammatory drugs, combination estrogen/progestin contraceptives, or progestin-only contraceptives are helpful and have few adverse effects.

Fertility-related considerations in endometriosis

  • Z. Khan
  • Medicine
    Abdominal Radiology
  • 2019
Overall, medical therapy is ineffective for endometriosis-related infertility; however, surgery may be fertility enhancing in women with minimal stage disease and inWomen with large endometRIomas.

Hormonal treatments for preventing recurrence of endometriomas

Most of them reported a beneficial impact on endometrioma recurrence by the usage of OC, PG, and GnRH analogs (GnRHa); however, conflicting results exist in the current literature about this topic.

Current Treatment of Endometrioma

Importance Ovarian endometrioma is the most common form of endometriosis. Laparoscopy is frequently chosen for its treatment because medical treatment alone is inadequate. However, the role of

Deep Endometriosis and Infertility: What Is the Impact of Surgery?

The review of the literature on the impact of deep endometriosis surgery on reproductive outcomes and pregnancy rates in women with and without prior infertility suggests that surgery may improve fertility outcomes.



Endometriosis: aetiology, pathogenesis and treatment.

There is little difference in efficacy between the different medications but their adverse effect profiles differ greatly, and it appears that gonadotropin-releasing hormone agonists, particularly when used with add-back estrogen, may be more acceptable to women than other treatments.

Ovulation suppression for endometriosis.

Ovulation suppression cannot be recommended as a standard therapy for endometriosis-associated infertility because of the significant period of amenorrhea associated with ovulation suppression, the lack of treatment benefit demonstrated and the adverse effects commonly associated with these treatments.

Management of endometriosis-associated infertility.

Endometriosis-associated infertility.

  • A. Haney
  • Medicine
    Bailliere's clinical obstetrics and gynaecology
  • 1993
The most promising therapeutic approach is to treat women with endometriosis-associated infertility with a non-specific cycle fecundity enhancing technique, such as controlled ovarian hyperstimulation with intrauterine insemination of capacitated sperm.

What is the optimal medical management of infertility and minor endometriosis? Analysis and future prospects.

Ovulation induction, perhaps with intrauterine insemination, does result in pregnancy rates higher than in control cycles, while stimulated IVF success rates are equivalent to those of other diagnostic groups.

Endometriosis and Inflammation in Infertility

This review provides an overview of recent data on the effects of endometriosis‐associated inflammation on fertility and suggests that inflammatory factors play a role in this endometiosis‐ associated reproductive failure.

Surgical management of endometriosis.

In case of moderate and severe endometriosis-associated infertility, the combined approach (operative laparoscopy with a gonadotropin-releasing hormone (GnRH) agonist) should be considered as 'first-line' treatment.

Treatment of endometriosis-associated infertility.

IVF and GIFT are often best for those who have failed other treatments, have advanced age, prolonged infertility, and/or multiple-factor infertility.

The relevance of the peritoneal fluid in endometriosis-associated infertility.

The mechanisms by which endometriosis may affect fertility are discussed, and an emphasis will be placed on the relevance of the peritoneal fluid.

Role of Laparoscopy in the Treatment of Endometriosis-Associated Infertility

Minimal/mild endometriosis benefited the most from laparoscopic manipulation when tubal adhesions were present, and IVF-ET outcome of patients who previously underwent laparoscopy was not influenced by preexisiting tubalAdhesions and endometRIosis.