Endometrial decidualization: of mice and men.

@article{Ramathal2010EndometrialDO,
  title={Endometrial decidualization: of mice and men.},
  author={Cyril Y. Ramathal and Indrani C. Bagchi and Robert K N Taylor and Milan K. Bagchi},
  journal={Seminars in reproductive medicine},
  year={2010},
  volume={28 1},
  pages={17-26}
}
In murine and human pregnancies, embryos implant by attaching to the luminal epithelium and invading into the stroma of the endometrium. Under the influence of the steroid hormones estrogen and progesterone, the stromal cells surrounding the implanting embryo undergo a remarkable transformation event. This process, known as decidualization, is an essential prerequisite for implantation. It comprises morphogenetic, biochemical, and vascular changes driven by the estrogen and progesterone… CONTINUE READING