Endometrial changes from short-term therapy with CDB-4124, a selective progesterone receptor modulator

@article{Ioffe2009EndometrialCF,
  title={Endometrial changes from short-term therapy with CDB-4124, a selective progesterone receptor modulator},
  author={Olga B. Ioffe and Richard J. Zaino and George L. Mutter},
  journal={Modern Pathology},
  year={2009},
  volume={22},
  pages={450-459}
}
Selective progesterone receptor modulators are a class of drugs with progesterone antagonist activity that may confer therapeutic benefit for reproductive disorders in premenopausal women. Endometrial structure, which is dynamically controlled by circulating sex hormones, is likely to be perturbed by progesterone receptor modulators through their progesterone antagonist properties. We examined endometrial histology in 58 premenopausal women treated with the progesterone receptor modulator CDB… CONTINUE READING

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