Endometrial cancer

  title={Endometrial cancer},
  author={S. Saso and J. Chatterjee and E. Georgiou and A. M. Ditri and J. Smith and S. Ghaem‐Maghami},
  journal={BMJ : British Medical Journal},
Division of Surgery, Oncology, Reproductive Biology and Anaesthetics, Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Hospital Campus, London W12 0NN, UK; Department of Biosurgery and Surgical Technology, Imperial College London; Carshalton, Surrey, UK; West London Gynaecological Cancer Centre, Queen Charlotte’s and Chelsea Hospital, Imperial College London, London; Imperial College London 
Gynecological Malignancies : Prevalence , Early Diagnosis and Preventive Strategies from a Physician ’ s Perspective
By 2025, 19.3 million new cancer cases are expected to be diagnosed each year. Gynaecological cancers include cancers of the female reproductive tract, namely of the cervix, ovary, fallopian tube,Expand
Palliative treatment of endometrial cancer: what is the role of anastrozole in elderly women?
The preliminary data suggested that the palliative use of anastrozole may be a suitable therapy for the proper management of early stages endometrial cancer in elderly women not suitable for surgical treatment with good compliance and tolerance. Expand
Fertility treatment and cancers-the eternal conundrum: a systematic review and meta-analysis.
Overall, FT does not significantly increase the incidence of breast, ovarian or endometrial cancer and may even reduce the incidence in no-FT groups and the results are reassuring. Expand
Frequency of endometrial cancer and atypical hyperplasia in infertile women undergoing hysteroscopic polypectomy
We aimed to determine the frequency of endometrial cancer in infertile women undergoing hysteroscopic endometrial polypectomy for endometrial polyps.
Endometrial Cancer
The uterus is the most common site of cancer in the female genital tract [ 1 , 2 ]. Most uterine cancers in the United States arise from the endometrium, which is the innermost layer of the uterineExpand
Does fertility treatment increase the risk of uterine cancer? A meta-analysis.
  • S. Saso, L. Louis, +7 authors M. Thum
  • Medicine
  • European journal of obstetrics, gynecology, and reproductive biology
  • 2015
A meta-analysis points to a non-deleterious effect of fertility drugs towards the development of uterine cancer, a conclusion strongly supported by the sub-group analysis. Expand
Type-II endometrial cancer: role of adipokines
This review presents the role of various adipokines involved and also the suitable modulators to treat Type-II endometrial cancer and the possible beneficial effects of adipokine modulator. Expand
The important application of thioridazine in the endometrial cancer.
All the data in the present study suggested that the THIO plus MPA might act as the suppressor of tumor growth in ECa by inhibiting the PI3K/AKT signal transduction pathway, which was mediated by PRB, DRD2 and EGFR. Expand
Robotic-assisted laparoscopic hysterectomy for women with endometrial cancer.
RALH appears advantageous for women treated for endometrial cancer in terms of post-operative complications and the use of the Clavien-Dindo classification of surgical outcomes for quality assessment is recommended. Expand
Loss of ARID1A Expression as a Favorable Prognostic Factor in Early-Stage Grade 3 Endometrioid Endometrial Carcinoma Patients
ARID1A expression status was a prognosticator for patients with early stage G3EEC without adjuvant therapy, whereas p53 and MMR expression status showed no impact on survival outcomes. Expand


Surgical management and postoperative treatment of endometrial carcinoma.
The surgical management of newly diagnosed disease is outlined and the risk factors that guide clinicians in the recommendation for postoperative adjuvant therapy are reviewed. Expand
Surgical pathologic spread patterns of endometrial cancer: A gynecologic oncology group study
Credence is added to the primary surgical approach with individualized postoperative therapy as indicated for Stage I carcinoma of the endometrium and multiple prognostic factors particularly grade and depth of invasion are related to extrauterine disease. Expand
Surgical Pathologic Spread Patterns of Endometrial Cancer
The surgical pathologic features of 621 patients with Stage I carcinoma of the endometrium are presented. All patients were treated with primary surgery consisting of total abdominal hysterectomy,Expand
[Cancer of the corpus uteri].
The outcome of this trial could help resolve a clinical dilemma facing thousands of endometrial cancer survivors and their physicians, according to the study's author. Expand
Accuracy of outpatient endometrial biopsy in the diagnosis of endometrial cancer: a systematic quantitative review
Objective To determine the accuracy of outpatient endometrial biopsy in diagnosing endometrial cancer in women with abnormal uterine bleeding.
Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study
The results show no evidence of benefit in terms of overall or recurrence-free survival for pelvic lymphadenectomy in women with early endometrial cancer and it cannot be recommended as routine procedure for therapeutic purposes outside of clinical trials. Expand
The influence of cytoreductive surgery on survival and morbidity in stage IVB endometrial cancer
The purpose of this study was to detect possible survival advantages of surgical cytoreduction and different adjuvant treatment regimens for stage IVB endometrial cancer patients, and also toExpand
Endometrial cancer.
Current concepts about epidemiology, pathology, pathogenesis, risk factors and prevention, diagnosis, staging, prognostic factors, treatment, and follow-up of endometrial cancer are reviewed. Expand
Laparoscopic hysterectomy in the treatment of endometrial cancer: a systematic review.
The short-term results of LS are equivalent or better than those achieved with open surgery, whereas the long- term results obtained by both seems equivalent but more studies are needed assessing this outcome. Expand
Worldwide burden of gynaecological cancer: the size of the problem.
The estimation of cancer burden is valuable to set up priorities for disease control and political will and advocacy to invest in healthcare infrastructure and human resources to improve service delivery and accessibility are vital to reduce the current burden in low- and medium-resource countries. Expand