Endometrial cancer: molecular and therapeutic aspects.

  title={Endometrial cancer: molecular and therapeutic aspects.},
  author={Panagiotis Tsikouras and Sofia Bouchlariotou and Nikolaos Vrachnis and Alexandros Dafopoulos and Georgios C Galazios and Roland Csorba and Georg Friedrich von Tempelhoff},
  journal={European journal of obstetrics, gynecology, and reproductive biology},
  volume={169 1},
Endometrial cancer (EC) is the most commonly diagnosed gynecologic malignancy. Although early-stage EC is effectively treated surgically, commonly without adjuvant therapy, the treatment of high-risk and advanced disease is more complex. Chemotherapy has evolved into an important modality in high-risk early-stage and advanced-stage disease, and in recurrent EC. Multi-institutional trials are in progress to better define optimal adjuvant treatment for subsets of patients, as well as the role of… CONTINUE READING
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