Endomesoderm specification in Caenorhabditis elegans and other nematodes.

@article{Maduro2006EndomesodermSI,
  title={Endomesoderm specification in Caenorhabditis elegans and other nematodes.},
  author={Morris F Maduro},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  year={2006},
  volume={28 10},
  pages={
          1010-22
        }
}
The endomesoderm gene regulatory network (GRN) of C. elegans is a rich resource for studying the properties of cell-fate-specification pathways. This GRN contains both cell-autonomous and cell non-autonomous mechanisms, includes network motifs found in other GRNs, and ties maternal factors to terminal differentiation genes through a regulatory cascade. In most cases, upstream regulators and their direct downstream targets are known. With the availability of resources to study close and distant… CONTINUE READING

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