Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs.

  title={Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs.},
  author={Franck Vazquez and Herv{\'e} Vaucheret and Ramya Rajagopalan and Christelle Lepers and Virginie Gasciolli and Allison C. Mallory and Jean-Louis Hilbert and David P. Bartel and Patrice Cr{\'e}t{\'e}},
  journal={Molecular cell},
  volume={16 1},
Here we describe a set of endogenous short interfering RNAs (siRNAs) in Arabidopsis, some of which direct the cleavage of endogenous mRNAs. These siRNAs correspond to both sense and antisense strands of a noncoding RNA (At2g27400) that apparently is converted to double-stranded RNA and then processed in 21 nt increments. These siRNAs differ from previously described regulatory small RNAs in two respects. First, they require components of the cosuppression pathway (RDR6 and SGS3) and also… CONTINUE READING
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