Endogenous steroids are responsible for lactoferrin-induced myelopoiesis in mice.

  title={Endogenous steroids are responsible for lactoferrin-induced myelopoiesis in mice.},
  author={Michał Zimecki and Jolanta Artym and Maja Kocięba},
  journal={Pharmacological reports : PR},
  volume={61 4},
Our previous study revealed that lactoferrin (LF) significantly increases mobilization of the myelocytic lineage in mice. The aim of our current investigation was to determine whether activation of the hypothalamic-pituitary-adrenal axis contributes to this phenomenon. We found that intravenous (iv) injection of LF (10 mg) caused a 48.8% increase in the circulating blood leukocyte count and increased the proportion of the myelocytic lineage (band forms, 10-fold and neutrophils, 2-fold) 24 h… CONTINUE READING
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Kruzel ML: Milk-derived proteins and peptides of potential therapeutic and nutritive value

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