Endogenous sex hormone levels in postmenopausal women undergoing carotid artery endarterectomy.
@article{Debing2007EndogenousSH, title={Endogenous sex hormone levels in postmenopausal women undergoing carotid artery endarterectomy.}, author={Erik Debing and Els Peeters and William Duquet and Kris Gustave Poppe and Brigitte Velkeniers and Pierre Van den Brande}, journal={European journal of endocrinology}, year={2007}, volume={156 6}, pages={ 687-93 } }
OBJECTIVE
To study the endogenous sex hormone levels in natural postmenopausal women and their association with the presence of internal carotid artery (ICA) atherosclerosis.
DESIGN
Case-control study
METHODS
We compared 56 patients with severe ICA atherosclerosis referred for carotid artery endarterectomy (CEA) with 56 age-matched control subjects free of severe atherosclerotic disease. The presence of atherosclerosis was determined by high-resolution B-mode ultrasound. Metabolic…Â
45 Citations
Endogenous sex steroids and cardio- and cerebro-vascular disease in the postmenopausal period.
- Medicine, BiologyEuropean journal of endocrinology
- 2012
Most studies support a beneficial role of endogenous estrogens and, probably, an adverse effect of androgens in the vasculature in postmenopausal women, but the described associations may not always be considered as causal.
Association of free testosterone and sex hormone binding globulin with metabolic syndrome and subclinical atherosclerosis but not blood pressure in hypertensive perimenopausal women
- Medicine, BiologyArchives of medical science : AMS
- 2016
Free testosterone and SHBG independently of menopause status are related to MS, and free testosterone is associated with worse metabolic profile, subclinical atherosclerosis and impaired diastolic function of the left ventricle.
Cardiovascular and sexual health effects of postmenopausal testosterone therapy
- Medicine, Biology
- 2015
It is suggested that short-term physiological testosterone does not adversely affect arterial stiffness and may improve markers of endothelial function and testosterone use was associated with reductions in HDL cholesterol and lipoprotein, but whether this has significant long-term CV effects remains unclear.
Low Free Testosterone Levels Are Associated With All-Cause and Cardiovascular Mortality in Postmenopausal Diabetic Women
- MedicineDiabetes Care
- 2011
In postmenopausal diabetic women referred for coronary angiography, low FT levels are independently associated with increased all-cause and cardiovascular mortality, but there is no association of TT and SHBG with mortality in diabetic post menopausal women.
STUDY OF ENDOGENOUS SEX HORMONES AND INFLAMMATION IN ELDERLY WOMEN WITH DIABETES MELLITUS
- Medicine, Biology
- 2014
Assessment of serum levels of endogenous sex hormones as well as high sensitive C -Reactive protein in elderly women with and without type 2 diabetes found significant association between inflammation and serum estradiol while there was no association betweeninflammatory and serum testosterone.
Sex steroids and markers of micro- and macrovascular damage among women and men from the general population.
- Medicine, BiologyEuropean journal of preventive cardiology
- 2021
A more androgenic profile was associated with more microvascular damage in both women and men, and the findings suggest that androgens might have distinct effects on the vasculature, depending on the vascular bed and stages of the atherosclerosis process.
Testosterone, SHBG and cardiovascular health in postmenopausal women
- Biology, MedicineInternational Journal of Impotence Research
- 2010
It is suggested that increased androgenicity, characterized by high testosterone and low SHBG levels, is associated with an adverse CVD risk factor profile in postmenopausal women, however, evidence for an association with cardiovascular events is lacking and it is uncertain whether the observed associations with endogenous testosterone have clinical implications regarding the use of post menopausal testosterone therapy.
Associations of blood lead levels with reproductive hormone levels in men and postmenopausal women: Results from the SPECT-China Study
- MedicineScientific reports
- 2016
BLLs were associated with reproductive hormone levels in the general population of Chinese men and postmenopausal women, which may have important implications for human health and Concerted efforts to reduce adult lead exposure are warranted.
Extremes of endogenous testosterone are associated with increased risk of incident coronary events in older women.
- MedicineThe Journal of clinical endocrinology and metabolism
- 2010
An optimal range of testosterone may exist for cardiovascular health in women, with increased risk of CHD events at low levels of testosterone overall and at high levels of the bioavailable fraction of testosterone.
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