Endogenous sex hormone levels and risk of cognitive decline in an older biracial cohort.

@article{Yaffe2007EndogenousSH,
  title={Endogenous sex hormone levels and risk of cognitive decline in an older biracial cohort.},
  author={Kristine Yaffe and Deborah L Barnes and Karla Lindquist and Jane A. Cauley and Eleanor M. Simonsick and Brenda P. Penninx and Suzanne Satterfield and Tamara M Harris and Steve Cummings},
  journal={Neurobiology of aging},
  year={2007},
  volume={28 2},
  pages={171-8}
}
BACKGROUND Older women treated with conjugated estrogens may have an increased risk of dementia, but the effect of naturally occurring sex hormones on cognition is not certain. METHODS Bioavailable estradiol and free testosterone level were obtained from 792 (55% men, 51% black) participants. We assessed cognition with the Modified Mini-Mental State Examination (3MS), Selective Reminding Test (SRT) and CLOX 1 at baseline and 2 years later. RESULTS Women in the lowest estradiol tertile were… CONTINUE READING