Endogenous secretory receptor for advanced glycation end product levels are inversely associated with HbA1c in type 2 diabetic patients.

@article{Katakami2006EndogenousSR,
  title={Endogenous secretory receptor for advanced glycation end product levels are inversely associated with HbA1c in type 2 diabetic patients.},
  author={Naoto Katakami and Munehide Matsuhisa and Hideaki Kaneto and Yoshimitsu Yamasaki},
  journal={Diabetes care},
  year={2006},
  volume={29 2},
  pages={469}
}
A dvanced glycation end products (AGEs) and their receptor (RAGE) system play an important role in the development of diabetic vascular complications (1,2). Recently, an endogenous secretory RAGE (esRAGE) has been identified as a novel splice variant, which lacks the transmembrane domain and is secreted in human sera. Interestingly, it was reported that esRAGE binds AGE ligands and neutralizes AGE actions (3). It is well known that type 2 diabetes is the most prevalent and serious metabolic… CONTINUE READING