Endogenous production of n-3 and n-6 fatty acids in mammalian cells.

@article{Morimoto2005EndogenousPO,
  title={Endogenous production of n-3 and n-6 fatty acids in mammalian cells.},
  author={Kohichi Morimoto and Alison L Van Eenennaam and Edward J Depeters and Juan F Medrano},
  journal={Journal of dairy science},
  year={2005},
  volume={88 3},
  pages={1142-6}
}
Polyunsaturated fatty acids (PUFA) are important components of mammalian diets, and the beneficial effects of n-3 PUFA on human development and cardiovascular health have been well documented. Caenorhabditis elegans is one of the few animals known to be able to produce linoleic (LA, 18:2n-6) and alpha-linolenic (ALA, 18:3n-3) essential fatty acids. These essential PUFA are generated by the action of desaturases that successively direct the conversion of monounsaturated fatty acids (MUFA) to… CONTINUE READING