Endogenous opioids, stress induced analgesia, and posttraumatic stress disorder.

  title={Endogenous opioids, stress induced analgesia, and posttraumatic stress disorder.},
  author={Bessel A. van der Kolk and Michael S. Greenberg and Scott P Orr and Roger K. Pitman},
  journal={Psychopharmacology bulletin},
  volume={25 3},
The hypothesis that the animal model of inescapable shock (IES) is an appropriate model for posttraumatic stress disorder (PTSD) predicts that re-exposure to a traumatic stressor will precipitate opioid-mediated stress-induced analgesia in people with PTSD. Eight Vietnam veterans with PTSD and eight matched veterans without PTSD viewed a combat videotape under naloxone and placebo conditions in a randomized double-blind crossover design. In the placebo condition, but not after naloxone, the… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
33 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 33 extracted citations

Similar Papers

Loading similar papers…