Endogenous opioid peptides contribute to associative LTP in the hippocampal CA3 region.

@article{Martinez2011EndogenousOP,
  title={Endogenous opioid peptides contribute to associative LTP in the hippocampal CA3 region.},
  author={Carlo O. Martinez and Viet H Do and Brian E. Derrick},
  journal={Neurobiology of learning and memory},
  year={2011},
  volume={96 2},
  pages={207-17}
}
The medial and lateral perforant path projections to the hippocampal CA3 region display distinct mechanisms of long-term potentiation (LTP) induction, N-methyl-d-aspartate (NMDA) and opioid receptor dependent, respectively. However, medial and lateral perforant path projections to the CA3 region display associative LTP with coactivation, suggesting that while they differ in receptors involved in LTP induction they may share common downstream mechanisms of LTP induction. Here we address this… CONTINUE READING