Endogenous opiates, opioids, and immune function: evolutionary brokerage of defensive behaviors.

Abstract

Recent empirical data have elucidated a compelling physiological basis for endogenously expressed, chemically authentic, morphine and its cognate mu3 and mu4 opiate receptors. Cellular "morphinergic" signaling is predominantly targeted to autocrine/paracrine regulatory processes and is reciprocally linked to stimulated production and release of the free… (More)
DOI: 10.1016/j.semcancer.2007.12.001

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