Endogenous modifiers of cigarette smoke exposure within the lung.

@article{Houghton2012EndogenousMO,
  title={Endogenous modifiers of cigarette smoke exposure within the lung.},
  author={A. M. Houghton},
  journal={Proceedings of the American Thoracic Society},
  year={2012},
  volume={9 2},
  pages={
          66-8
        }
}
Cigarette smoke exposure generates both acute and chronic inflammatory cell infiltrates that are operative in numerous pulmonary disorders. Cigarette smoke induces a complex signaling cascade within the lung mediated by epithelial cells, lymphocytes, macrophages, and others. The net result is a destructive and self-perpetuating inflammatory environment that is capable of creating lung diseases such as emphysema, while simultaneously fueling lung tumor growth using both matrix-dependent and… CONTINUE READING

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