Endogenous kappa-opioid mediation of stress-induced potentiation of ethanol-conditioned place preference and self-administration

Abstract

Exposure to inescapable stressors increases both the rewarding properties and self-administration of cocaine through the signaling of the kappa-opioid receptor (KOR), but the effect of this signaling on other reinforcing agents remains unclear. The objective of this study is to test the hypothesis that signaling of the KOR mediates the forced swim stress… (More)
DOI: 10.1007/s00213-010-1844-5

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@article{Sperling2010EndogenousKM, title={Endogenous kappa-opioid mediation of stress-induced potentiation of ethanol-conditioned place preference and self-administration}, author={Robin E. Sperling and Stacey M. Gomes and Elizabeth I. Sypek and Amanda N. Carey and Jay P. McLaughlin}, journal={Psychopharmacology}, year={2010}, volume={210}, pages={199-209} }