Endogenous histamine in the medial septum-diagonal band complex increases the release of acetylcholine from the hippocampus: a dual-probe microdialysis study in the freely moving rat.

@article{Bacciottini2002EndogenousHI,
  title={Endogenous histamine in the medial septum-diagonal band complex increases the release of acetylcholine from the hippocampus: a dual-probe microdialysis study in the freely moving rat.},
  author={Lucia Bacciottini and Maria Beatrice Passani and Lisa Giovannelli and Iacopo Cangioli and Pier Francesco Mannaioni and Walter Schunack and Patrizio Blandina},
  journal={The European journal of neuroscience},
  year={2002},
  volume={15 10},
  pages={1669-80}
}
The effects of histaminergic ligands on both ACh spontaneous release from the hippocampus and the expression of c-fos in the medial septum-diagonal band (MSA-DB) of freely moving rats were investigated. Because the majority of cholinergic innervation to the hippocampus is provided by MSA-DB neurons, we used the dual-probe microdialysis technique to apply drugs to the MSA-DB and record the induced effects in the projection area. Perfusion of MSA-DB with high-KCl medium strongly stimulated… CONTINUE READING

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