Endogenous haemopoietic growth factors in neutropenia and infection.

  title={Endogenous haemopoietic growth factors in neutropenia and infection.},
  author={Jonathon Cebon and Judith E. Layton and Darryl W. Maher and George Morstyn},
  journal={British journal of haematology},
  volume={86 2},
Haemopoietic growth factors (HGFs) are being administered to patients with neutropenic fever; however, little is known about the endogenous HGF response in these patients. Specific assays were used to study four HGFs, granulocyte (G-) CSF, granulocyte-macrophage (GM-) CSF, macrophage (M-) CSF and interleukin (IL-) 6 levels in the blood of patients with neutropenic fever (46 episodes). For comparison, levels were also measured in three control populations: normals (20), afebrile neutropenic (14… CONTINUE READING